Pathobiology of brain metastases.

Pathobiology and Emerging Targeted Therapies in Brain Metastases: Summary of Preusser et al, Acta Neuropathol 2012

Dosimetric comparison of two different whole brain radiotherapy techniques in patients with brain metastases: How to decrease lens dose?

Background: Palliative whole brain radiotherapy (WBRT) has been the standard treatment for brain metastases. Ionizing radiation is known to be one of the most potent cataractogenic agents. We aimed to evaluate two different radiotherapy techniques with respect to the doses received by the organs at risk (OAR) in patients with brain metastasis who undergone WBRT. Materials and Methods: Ten conse...

Papillary thyroid cancer with metastases to brain, lung and kidney: A case of dosimetry proven privilege of surgical resection of organ metastases

A 45-year-old woman presented with a headache and visual complaints. Brain MRI revealed a large mass in the right occipital cortex. The tumor was surgically removed and pathological examination showed papillary carcinoma originating from thyroid gland. She had a history of thyroid surgery 27 years ago indicating papillary thyroid cancer with central neck lymph node involvement followed by no ad...

بررسی بقا بر اساس سیستم نمره‌بندی GPA در مبتلایان به متاستازهای مغزی درمان شده با رادیوسرجری گامانایف

Abstract Background: This study was done to define the role of Graded Prognostic Assessment (GPA) score for predicting overall survival in patients diagnosed with brain metastases undergoing Gamma-knife radiosurgery. Materials and methods: Patients diagnosed with brain metastases who were candidates for Gamma-knife radiosurgery entered this cross sectional study between 2003 and 2011. Clin...

بکارگیری مدل مخاطرات متناسب کاکس در شناسایی عوامل موثر بر بقای بیماران مبتلا به متاستاز مغزی

Abstract Background : The aim of this study is to determine of risk factors in patients with brain metastases, and prognostic factors affecting survival of patients by using the Cox proportional hazards model. Methods : This descriptive - analytic retrospective study was performed on 197 patients with brain metastases who Referred to Shahid Ramezanzadeh Radiation Center, Yazd, Iran. Several ris...